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Three-dimensional model of the human platelet integrin α(IIb)β(3) based on electron cryomicroscopy and x-ray crystallography
Integrins are a large family of heterodimeric transmembrane signaling proteins that affect diverse biological processes such as development, angiogenesis, wound healing, neoplastic transformation, and thrombosis. We report here the three-dimensional structure at 20-Å resolution of the unliganded, lo...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137836/ https://ncbi.nlm.nih.gov/pubmed/12388784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212498199 |
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