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Analysis and classification of 304 mutant alleles in patients with type 1 and type 3 Gaucher disease.

Gaucher disease results from the inherited deficiency of the enzyme glucocerebrosidase (EC 3.2.1.45). Although >100 mutations in the gene for human glucocerebrosidase have been described, most genotype-phenotype studies have focused upon screening for a few common mutations. In this study, we use...

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Autors principals: Koprivica, V, Stone, D L, Park, J K, Callahan, M, Frisch, A, Cohen, I J, Tayebi, N, Sidransky, E
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378059/
https://ncbi.nlm.nih.gov/pubmed/10796875
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