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Identification of uniparental disomy following prenatal detection of Robertsonian translocations and isochromosomes.

Rearrangements of the acrocentric chromosomes (Robertsonian translocations and isochromosomes) are associated with an increased risk of aneuploidy. Given this, and the large number of reported cases of uniparental disomy (UPD) associated with an acrocentric rearrangement, carriers are presumed to be...

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Bibliografische gegevens
Hoofdauteurs: Berend, S A, Horwitz, J, McCaskill, C, Shaffer, L G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378034/
https://ncbi.nlm.nih.gov/pubmed/10775524
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