Severe hepatic fibrosis in Schistosoma mansoni infection is controlled by a major locus that is closely linked to the interferon-gamma receptor gene.

Lethal disease due to hepatic periportal fibrosis occurs in 2%-10% of subjects infected by Schistosoma mansoni in endemic regions such as Sudan. It is unknown why few infected individuals present with severe disease, and inherited factors may play a role in fibrosis development. Schistosoma mansoni...

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Detalhes bibliográficos
Main Authors: Dessein, A J, Hillaire, D, Elwali, N E, Marquet, S, Mohamed-Ali, Q, Mirghani, A, Henri, S, Abdelhameed, A A, Saeed, O K, Magzoub, M M, Abel, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377977/
https://ncbi.nlm.nih.gov/pubmed/10441577
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