Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum.

To determine the prevalence of early-onset Alzheimer disease (EOAD) and of autosomal dominant forms of EOAD (ADEOAD), we performed a population-based study in the city of Rouen (426,710 residents). EOAD was defined as onset of disease at age <61 years, and ADEOAD was defined as the occurrence of...

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Autores principales: Campion, D, Dumanchin, C, Hannequin, D, Dubois, B, Belliard, S, Puel, M, Thomas-Anterion, C, Michon, A, Martin, C, Charbonnier, F, Raux, G, Camuzat, A, Penet, C, Mesnage, V, Martinez, M, Clerget-Darpoux, F, Brice, A, Frebourg, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377972/
https://ncbi.nlm.nih.gov/pubmed/10441572
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