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Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

To define the early events that determine the outcome of acute hepatitis C virus (HCV) infection, we compared the course of viremia with the peripheral and intrahepatic T cell response and intrahepatic cytokine profile in six acutely infected chimpanzees. Three different outcomes were observed after...

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Autori principali: Thimme, Robert, Bukh, Jens, Spangenberg, Hans Christian, Wieland, Stefan, Pemberton, Janell, Steiger, Carola, Govindarajan, Sugantha, Purcell, Robert H., Chisari, Francis V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC137773/
https://ncbi.nlm.nih.gov/pubmed/12441397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202608299
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