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Combined linkage and association sib-pair analysis for quantitative traits.

An extension to current maximum-likelihood variance-components procedures for mapping quantitative-trait loci in sib pairs that allows a simultaneous test of allelic association is proposed. The method involves modeling of the allelic means for a test of association, with simultaneous modeling of th...

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Bibliografische gegevens
Hoofdauteurs: Fulker, D W, Cherny, S S, Sham, P C, Hewitt, J K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377724/
https://ncbi.nlm.nih.gov/pubmed/9915965
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