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Neuroprotective autoimmunity: Naturally occurring CD4(+)CD25(+) regulatory T cells suppress the ability to withstand injury to the central nervous system

The ability of rats or mice to withstand the consequences of injury to myelinated axons in the CNS was previously shown to depend on the ability to manifest a T cell-mediated protective immune response, which is amenable to boosting by myelin-specific T cells. Here we show that this ability, assesse...

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Autori principali: Kipnis, Jonathan, Mizrahi, Tal, Hauben, Ehud, Shaked, Iftach, Shevach, Ethan, Schwartz, Michal
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC137766/
https://ncbi.nlm.nih.gov/pubmed/12429857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232565399
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