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Disequilibrium likelihoods for fine-scale mapping of a rare allele.

Genetic linkage studies based on pedigree data have limited resolution, because of the relatively small number of segregations. Disequilibrium mapping, which uses population associations to infer the location of a disease mutation, provides one possible strategy for narrowing the candidate region. T...

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Bibliografske podrobnosti
Main Authors: Graham, J, Thompson, E A
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377562/
https://ncbi.nlm.nih.gov/pubmed/9792879
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