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Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone.

Paget disease of bone, or "osteitis deformans," is a bone disorder characterized by rapid bone remodeling resulting in abnormal bone formation. It is the second most common metabolic bone disease after osteoporosis, affecting 3%-5% of subjects aged >40 years. Recent evidence suggests th...

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Main Authors: Nellissery, M J, Padalecki, S S, Brkanac, Z, Singer, F R, Roodman, G D, Unni, K K, Leach, R J, Hansen, M F
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377407/
https://ncbi.nlm.nih.gov/pubmed/9718349
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