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Somatic mosaicism: a common cause of classic disease in tumor-prone syndromes? Lessons from type 2 neurofibromatosis.

Blood samples from 125 families with classic type 2 neurofibromatosis with bilateral vestibular schwannomas were analyzed for mutations in the NF2 gene. Causative mutations were identified in 52 families. In five families, the first affected individual in the family (the index case) was a mosaic for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Evans, D G, Wallace, A J, Wu, C L, Trueman, L, Ramsden, R T, Strachan, T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377392/
https://ncbi.nlm.nih.gov/pubmed/9718334
Etiketak: Etiketa erantsi
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