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The power to detect linkage in complex disease by means of simple LOD-score analyses.

Maximum-likelihood analysis (via LOD score) provides the most powerful method for finding linkage when the mode of inheritance (MOI) is known. However, because one must assume an MOI, the application of LOD-score analysis to complex disease has been questioned. Although it is known that one can legi...

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Dettagli Bibliografici
Autori principali: Greenberg, D A, Abreu, P, Hodge, S E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377386/
https://ncbi.nlm.nih.gov/pubmed/9718328
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