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Assignment of the disease locus for lethal congenital contracture syndrome to a restricted region of chromosome 9q34, by genome scan using five affected individuals.

Lethal congenital contracture syndrome (LCCS) is an autosomal recessive disease leading to death before the 32d gestational week. It is characterized by the fetal akinesia phenotype, with highly focused degeneration of motoneurons in the spinal cord as the main neuropathological finding. We report h...

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Detalhes bibliográficos
Main Authors: Mäkelä-Bengs, P, Järvinen, N, Vuopala, K, Suomalainen, A, Ignatius, J, Sipilä, M, Herva, R, Palotie, A, Peltonen, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377309/
https://ncbi.nlm.nih.gov/pubmed/9683599
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