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Frequency and carrier risk associated with common BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer patients.

Based on breast cancer families with multiple and/or early-onset cases, estimates of the lifetime risk of breast cancer in carriers of BRCA1 or BRCA2 mutations may be as high as 85%. The risk for individuals not selected for family history or other risk factors is uncertain. We determined the freque...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fodor, F H, Weston, A, Bleiweiss, I J, McCurdy, L D, Walsh, M M, Tartter, P I, Brower, S T, Eng, C M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377227/
https://ncbi.nlm.nih.gov/pubmed/9634504
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