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An alternative route for multistep tumorigenesis in a novel case of hereditary renal cell cancer and a t(2;3)(q35;q21) chromosome translocation.

Through allele-segregation and loss-of-heterozygosity analyses, we demonstrated loss of the translocation-derivative chromosome 3 in five independent renal cell tumors of the clear-cell type, obtained from three members of a family in which a constitutional t(2;3)(q35;q21) was encountered. In additi...

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Detalhes bibliográficos
Main Authors: Bodmer, D, Eleveld, M J, Ligtenberg, M J, Weterman, M A, Janssen, B A, Smeets, D F, de Wit, P E, van den Berg, A, van den Berg, E, Koolen, M I, Geurts van Kessel, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377167/
https://ncbi.nlm.nih.gov/pubmed/9585616
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