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Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin

We report studies of hydration dynamics at the surface of the enzyme protein bovine pancreatic α-chymotrypsin. The probe is the well known 1-anilinonaphthalene-8-sulfonate, which binds selectively in the native state of the protein, not the molten globule, as shown by x-ray crystallography. With fem...

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Bibliografiske detaljer
Main Authors: Pal, Samir Kumar, Peon, Jorge, Zewail, Ahmed H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137710/
https://ncbi.nlm.nih.gov/pubmed/12427971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242600399
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