A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility.

Premature ovarian failure (POF) is a defect of ovarian development and is characterized by primary or secondary amenorrhea, with elevated levels of serum gonadotropins, or by early menopause. The disorder has been attributed to various causes, including rearrangements of a large "critical regio...

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Detalhes bibliográficos
Main Authors: Bione, S, Sala, C, Manzini, C, Arrigo, G, Zuffardi, O, Banfi, S, Borsani, G, Jonveaux, P, Philippe, C, Zuccotti, M, Ballabio, A, Toniolo, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1376955/
https://ncbi.nlm.nih.gov/pubmed/9497258
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