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Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

To provide a global analysis of gene expression in the aging heart, we monitored the expression of 9,977 genes simultaneously in 5- and 30-month-old male B6C3F(1) mice by using high-density oligonucleotide microarrays and several statistical techniques. Aging was associated with transcriptional alte...

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Hlavní autoři: Lee, Cheol-Koo, Allison, David B., Brand, Jaap, Weindruch, Richard, Prolla, Tomas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137532/
https://ncbi.nlm.nih.gov/pubmed/12419851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232308999
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