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A single point mutation in ecdysone receptor leads to increased ligand specificity: Implications for gene switch applications
The ecdysone receptor (EcR), a member of the nuclear receptor superfamily, plays an important role in regulating development and reproduction in insects. The EcR binds to ecdysteroids and regulates transcription of genes that contain ecdysone response elements. The EcR has been used to develop induc...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137484/ https://ncbi.nlm.nih.gov/pubmed/12411578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222278999 |
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