Site-Specific PEGylation of Engineered Cysteine Analogs of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) stimulates proliferation of hematopoietic cells of the macrophage and granulocyte lineages and is used clinically to treat neutropenia and other myeloid disorders. Because of its short circulating half-life GM-CSF is administered to patients...

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Bibliographic Details
Main Authors: Doherty, Daniel H., Rosendahl, Mary S., Smith, Darin J., Hughes, Jennifer M., Chlipala, Elizabeth A., Cox, George N.
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373678/
https://ncbi.nlm.nih.gov/pubmed/16173810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc050172r
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