Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage

Mutations in the transcription factor Sox10 or Endothelin Receptor B (Ednrb) result in Waardenburg Syndrome Type IV (WS-IV), which presents with deficiencies of neural crest derived melanocytes (hypopigmentation) and enteric ganglia (hypoganglionosis). As Sox10 and Ednrb are expressed in mouse migra...

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Main Authors: Hakami, Ramin Mollaaghababa, Hou, Ling, Baxter, Laura, Loftus, Stacie, Southard-Smith, E. Michelle, Incao, Arturo, Cheng, Jun, Pavan, William J.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373669/
https://ncbi.nlm.nih.gov/pubmed/16412618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2005.11.004
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