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Altered aggregation properties of mutant γ-crystallins cause inherited cataract

Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key event in cataract formation involving altered γ-crysta...

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Main Authors: Sandilands, Aileen, Hutcheson, Aileen M., Long, Heather A., Prescott, Alan R., Vrensen, Gijs, Löster, Jana, Klopp, Norman, Lutz, Raimund B., Graw, Jochen, Masaki, Shigeo, Dobson, Christopher M., MacPhee, Cait E., Quinlan, Roy A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC137201/
https://ncbi.nlm.nih.gov/pubmed/12426373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf609
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