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Altered aggregation properties of mutant γ-crystallins cause inherited cataract
Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key event in cataract formation involving altered γ-crysta...
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Autori principali: | , , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Oxford University Press
2002
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137201/ https://ncbi.nlm.nih.gov/pubmed/12426373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf609 |
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