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Characterization of DNA synthesis catalyzed by bacteriophage T4 replication complexes reconstituted on synthetic circular substrates

Replication complexes were reconstituted using the eight purified bacteriophage T4 replication proteins and synthetic circular 70-, 120- or 240-nt DNA substrates annealed to a leading-strand primer. To differentiate leading strands from lagging strands, the circular parts of the substrates lacked dC...

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Bibliographic Details
Main Authors: Kadyrov, Farid A., Drake, John W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC137140/
https://ncbi.nlm.nih.gov/pubmed/12384585
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