Slipped-strand DNAs formed by long (CAG)·(CTG) repeats: slipped-out repeats and slip-out junctions

The disease-associated expansion of (CTG)·(CAG) repeats is likely to involve slipped-strand DNAs. There are two types of slipped DNAs (S-DNAs): slipped homoduplex S-DNAs are formed between two strands having the same number of repeats; and heteroduplex slipped intermediates (SI-DNAs) are formed betw...

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Main Authors: Pearson, Christopher E., Tam, Mandy, Wang, Yuh-Hwa, Montgomery, S. Erin, Dar, Arvin C., Cleary, John D., Nichol, Kerrie
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC137136/
https://ncbi.nlm.nih.gov/pubmed/12384601
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