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Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1

Aptamers, small oligonucleotides derived from an in vitro evolution process called SELEX, are promising therapeutic and diagnostic agents. Although very effective in vitro, only a few examples are available showing their potential in vivo. We have analyzed the effect of a well characterized pseudokn...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chaloin, Laurent, Lehmann, Maik Jörg, Sczakiel, Georg, Restle, Tobias
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC137107/
https://ncbi.nlm.nih.gov/pubmed/12235384
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