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The bunyavirus nucleocapsid protein is an RNA chaperone: Possible roles in viral RNA panhandle formation and genome replication

Cellular RNA chaperones are crucial for the genesis of correctly folded functional RNAs. Using several complementary in vitro assays we find that the bunyavirus nucleocapsid protein (N) is an RNA chaperone. In the Bunyaviridae genomic RNA is in stable “panhandle” formation that arises through the hy...

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Autors principals: MIR, M. AYOUB, PANGANIBAN, ANTONITO T.
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2006 by RNA Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370907/
https://ncbi.nlm.nih.gov/pubmed/16428606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2101906
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