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A base-specific recognition signal in the 5′ consensus sequence of rotavirus plus-strand RNAs promotes replication of the double-stranded RNA genome segments

Replication of the segmented double-stranded (ds)RNA genome of rotavirus requires the viral RNA-dependent RNA polymerase (RdRP) to use 11 different (+)RNAs as templates for (−) strand synthesis. Complementary sequences proximal to the 5′ and 3′ termini are predicted to direct cyclization of the (+)R...

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Bibliografiske detaljer
Main Authors: TORTORICI, M. ALEJANDRA, SHAPIRO, BRUCE A., PATTON, JOHN T.
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2006 by RNA Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370893/
https://ncbi.nlm.nih.gov/pubmed/16301600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2122606
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