Accessibility of 18S rRNA in human 40S subunits and 80S ribosomes at physiological magnesium ion concentrations—implications for the study of ribosome dynamics

Protein biosynthesis requires numerous conformational rearrangements within the ribosome. The structural core of the ribosome is composed of RNA and is therefore dependent on counterions such as magnesium ions for function. Many steps of translation can be compromised or inhibited if the concentrati...

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Main Authors: SHENVI, CHRISTINA L., DONG, KEN C., FRIEDMAN, ERIC M., HANSON, JEFFREY A., CATE, JAMIE H.D.
Format: Artigo
Language:Inglês
Published: Copyright 2005 by RNA Society 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370877/
https://ncbi.nlm.nih.gov/pubmed/16314459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2192805
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