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Yeast Puf3 mutants reveal the complexity of Puf-RNA binding and identify a loop required for regulation of mRNA decay
The eukaryotic Puf proteins regulate mRNA translation and degradation by binding the 3′ untranslated regions of target mRNAs. Crystal structure analysis of a human Puf bound to RNA suggested a modular mode of binding, with specific amino acids within each of eight repeat domains contacting a single...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370852/ https://ncbi.nlm.nih.gov/pubmed/16244132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2168505 |
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