Binding of misacylated tRNAs to the ribosomal A site

To test whether the ribosome displays specificity for the esterified amino acid and the tRNA body of an aminoacyl-tRNA (aa-tRNA), the stabilities of 4 correctly acylated and 12 misacylated tRNAs in the ribosomal A site were determined. By introducing the GAC (valine) anticodon into each tRNA, a cons...

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Bibliographic Details
Main Authors: DALE, TARAKA, UHLENBECK, OLKE C.
Format: Artigo
Language:Inglês
Published: Copyright 2005 by RNA Society 2005
Subjects:
Letter to the Editor
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370846/
https://ncbi.nlm.nih.gov/pubmed/16244128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2130505
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