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Weighted sequence motifs as an improved seeding step in microRNA target prediction algorithms

We present a new microRNA target prediction algorithm called TargetBoost, and show that the algorithm is stable and identifies more true targets than do existing algorithms. TargetBoost uses machine learning on a set of validated microRNA targets in lower organisms to create weighted sequence motifs...

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Detalhes bibliográficos
Main Authors: SÆTROM, OLA, SNØVE, OLA, SÆTROM, PÅL
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370784/
https://ncbi.nlm.nih.gov/pubmed/15928346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7290705
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