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In vivo aggregation properties of the nuclear poly(A)-binding protein PABPN1

A broad range of degenerative diseases is associated with intracellular inclusions formed by toxic, aggregation-prone mutant proteins. Intranuclear inclusions constitute a pathological hallmark of oculopharyngeal muscular dystrophy (OPMD), a dominantly inherited disease caused by (GCG) repeat expans...

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Autores principales: TAVANEZ, JOÃO PAULO, CALADO, PATRICIA, BRAGA, JOSÉ, LAFARGA, MIGUEL, CARMO-FONSECA, MARIA
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2005 by RNA Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370760/
https://ncbi.nlm.nih.gov/pubmed/15811916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7217105
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