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Conserved spacing between the box C/D and C′/D′ RNPs of the archaeal box C/D sRNP complex is required for efficient 2′-O-methylation of target RNAs

RNA-guided nucleotide modification complexes direct the post-transcriptional nucleotide modification of both archaeal and eukaryotic RNAs. We have previously demonstrated that efficient 2′-O-methylation activity guided by an in vitro reconstituted archaeal box C/D sRNP requires juxtaposed box C/D an...

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Autors principals: TRAN, ELIZABETH, ZHANG, XINXIN, LACKEY, LELA, MAXWELL, E. STUART
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2005 by RNA Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370718/
https://ncbi.nlm.nih.gov/pubmed/15661846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7223405
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