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Alternative splicing induced by nonsense mutations in the immunoglobulin μ VDJ exon is independent of truncation of the open reading frame

In addition to triggering nonsense-mediated mRNA decay (NMD), premature translation-termination codons (PTCs) frequently induce alternative splicing, an observation referred to as nonsense-associated alternative splicing (NAS). In many cases, NAS is induced because the nonsense mutation alters a spl...

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Detalhes bibliográficos
Main Authors: BÜHLER, MARC, MÜHLEMANN, OLIVER
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370703/
https://ncbi.nlm.nih.gov/pubmed/15613538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7183805
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