Evolution of Bacteriophage in Continuous Culture: a Model System To Test Antiviral Gene Therapies for the Emergence of Phage Escape Mutants

The emergence of viral escape mutants is usually a highly undesirable phenomenon. This phenomenon is frequently observed in antiviral drug applications for the treatment of viral infections and can undermine long-term therapeutic success. Here, we propose a strategy for evaluating a given antiviral...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lindemann, Björn F., Klug, Christian, Schwienhorst, Andreas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Recombination and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11992006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.11.5784-5792.2002
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