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Aptamer redesigned tRNA is nonfunctional and degraded in cells
An RNA aptamer derived from tRNA(Gln) isolated in vitro and a rationally redesigned tRNA(Gln) were used to address the relationship between structure and function of tRNA(Gln) aminoacylation in Escherichia coli. Two mutant tRNA(Gln) sequences were studied: an aptamer that binds 26-fold tighter to gl...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Copyright 2004 by RNA Society
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370512/ https://ncbi.nlm.nih.gov/pubmed/14681579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5165804 |
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