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Perturbation of transcription elongation influences the fidelity of internal exon inclusion in Saccharomyces cerevisiae

Unknown mechanisms exist to ensure that exons are not skipped during biogenesis of mRNA. Studies have connected transcription elongation with regulated alternative exon inclusion. To determine whether the relative rates of transcription elongation and spliceosome assembly might play a general role i...

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Autors principals: HOWE, KENNETH JAMES, KANE, CAROLINE M., ARES, MANUEL
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2003 by RNA Society 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370465/
https://ncbi.nlm.nih.gov/pubmed/12869710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5390803
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