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Stop codon suppression via inhibition of eRF1 expression

In humans, recognition of a stop codon by protein release factor eRF1 leads to release of the nascent peptide from the ribosome. Although efficient eRF1 activity is usually desirable, numerous pathologies result from eRF1 recognition of premature stop mutations in essential genes. In these cases, de...

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Autori principali: CARNES, JASON, JACOBSON, MARTY, LEINWAND, LESLIE, YARUS, MICHAEL
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2003 by RNA Society 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370432/
https://ncbi.nlm.nih.gov/pubmed/12756323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5280103
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