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Elevated activity of the large form of ADAR1 in vivo: Very efficient RNA editing occurs in the cytoplasm
Mammalian cells express small and large forms of the RNA editing enzyme ADAR1, referred to as ADAR1-S and ADAR1-L, respectively. Here we observed that ADAR1-L was >70-fold more active than was ADAR1-S when assayed with a substrate that could be edited in either the nucleus or cytoplasm, and was a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2003 by RNA Society
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370424/ https://ncbi.nlm.nih.gov/pubmed/12702817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5160403 |
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