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Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila

RNA interference (RNAi) designates the multistep process by which double-stranded RNA induces the silencing of homologous endogenous genes. Some aspects of RNAi appear to be conserved throughout evolution, including the processing of trigger dsRNAs into small 21–23-bp siRNAs and their use to guide t...

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Autors principals: ROIGNANT, JEAN-YVES, CARRÉ, CLÉMENT, MUGAT, BRUNO, SZYMCZAK, DIMITRI, LEPESANT, JEAN-ANTOINE, ANTONIEWSKI, CHRISTOPHE
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2003 by RNA Society 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370397/
https://ncbi.nlm.nih.gov/pubmed/12592004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2154103
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