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Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing.

The goal of functional genomics is to determine the function of each protein encoded by an organism. Typically, this is done by inactivating individual genes and, subsequently, analyzing the phenotype of the modified organisms. In higher eukaryotes, where a tremendous amount of alternative splicing...

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Bibliographic Details
Main Authors: Celotto, Alicia M, Graveley, Brenton R
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370291/
https://ncbi.nlm.nih.gov/pubmed/12088145
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