Efficient aminoacylation of the tRNA(Ala) acceptor stem: dependence on the 2:71 base pair.

Specific aminoacylation by aminoacyl-tRNA synthetases requires accurate recognition of cognate tRNA substrates. In the case of alanyl-tRNA synthetase (AlaRS), RNA duplexes that mimic the acceptor stem of the tRNA are efficient substrates for aminoacylation in vitro. It was previously shown that reco...

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Main Authors: Beuning, Penny J, Nagan, Maria C, Cramer, Christopher J, Musier-Forsyth, Karin, Gelpí, Josep-Lluis, Bashford, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370286/
https://ncbi.nlm.nih.gov/pubmed/12022232
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