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A hammerhead ribozyme substrate and reporter for in vitro kinetoplastid RNA editing.

Current in vitro assays for RNA editing in kinetoplastids directly examine the products generated by incubation of pre-mRNA substrate with guide RNA (gRNA) and mitochondrial (mt) extract. RNA editing substrates that are modeled on hammerhead ribozymes were designed with catalytic cores that containe...

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Bibliografiske detaljer
Main Authors: Wang, Bingbing, Salavati, Reza, Heidmann, Stefan, Stuart, Kenneth
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370276/
https://ncbi.nlm.nih.gov/pubmed/11991648
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