RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs.

In animals and protozoa, gene-specific double-stranded RNA (dsRNA) triggers degradation of homologous cellular RNAs, a phenomenon known as RNA interference (RNAi). In vitro and in vivo dsRNA is processed by a nuclease to produce 21-25-nt small interfering RNAs (siRNAs) that guide target RNA degradat...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Djikeng, A, Shi, H, Tschudi, C, Ullu, E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2001
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370195/
https://ncbi.nlm.nih.gov/pubmed/11720282
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