Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.

prp12-1 is one of the mutants defective in pre-mRNA splicing at a nonpermissive temperature in Schizosaccharomyces pombe. We found that the prp12+ gene encodes a protein highly homologous with a human splicing factor, SAP130/SF3b130, a subunit of a U2 snRNP-associated complex SF3b. Prp12p was shown...

Full description

Saved in:
Bibliographic Details
Main Authors: Habara, Y, Urushiyama, S, Shibuya, T, Ohshima, Y, Tani, T
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370119/
https://ncbi.nlm.nih.gov/pubmed/11350031
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items