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Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.

prp12-1 is one of the mutants defective in pre-mRNA splicing at a nonpermissive temperature in Schizosaccharomyces pombe. We found that the prp12+ gene encodes a protein highly homologous with a human splicing factor, SAP130/SF3b130, a subunit of a U2 snRNP-associated complex SF3b. Prp12p was shown...

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Bibliografische gegevens
Hoofdauteurs: Habara, Y, Urushiyama, S, Shibuya, T, Ohshima, Y, Tani, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370119/
https://ncbi.nlm.nih.gov/pubmed/11350031
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