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The hammerhead cleavage reaction in monovalent cations.

Recently, Murray et al. (Chem Biol, 1998, 5:587-595) found that the hammerhead ribozyme does not require divalent metal ions for activity if incubated in high (> or =1 M) concentrations of monovalent ions. We further characterized the hammerhead cleavage reaction in the absence of divalent metal....

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Bibliographic Details
Main Authors: Curtis, E A, Bartel, D P
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370108/
https://ncbi.nlm.nih.gov/pubmed/11345433
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