Substitution in the Murine Nectin1 Receptor of a Single Conserved Amino Acid at a Position Distal from the Herpes Simplex Virus gD Binding Site Confers High-Affinity Binding to gD

By analogy with its human nectin1 counterpart, murine nectin1 serves as a cellular receptor for the entry of herpes simplex virus (HSV) into murine cells. HSV entry mediated by either receptor is dependent on the viral glycoprotein D (gD). Whereas human nectin1 binds gD at high affinity and in a sat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Menotti, Laura, Casadio, Rita, Bertucci, Carlo, Lopez, Marc, Campadelli-Fiume, Gabriella
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11991974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.11.5463-5471.2002
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