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An early transition state for folding of the P4-P6 RNA domain.

Tertiary folding of the 160-nt P4-P6 domain of the Tetrahymena group I intron RNA involves burying of substantial surface area, providing a model for the folding of other large RNA domains involved in catalysis. Stopped-flow fluorescence was used to monitor the Mg2+-induced tertiary folding of pyren...

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Bibliografski detalji
Glavni autori: Silverman, S K, Cech, T R
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370074/
https://ncbi.nlm.nih.gov/pubmed/11233973
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