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Suppression of eukaryotic translation termination by selected RNAs.

Using selection-amplification, we have isolated RNAs with affinity for translation termination factors eRF1 and eRF1.eRF3 complex. Individual RNAs not only bind, but inhibit eRF1-mediated release of a model nascent chain from eukaryotic ribosomes. There is also significant but weaker inhibition of e...

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Detalhes bibliográficos
Main Authors: Carnes, J, Frolova, L, Zinnen, S, Drugeon, G, Phillippe, M, Justesen, J, Haenni, A L, Leinwand, L, Kisselev, L L, Yarus, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370017/
https://ncbi.nlm.nih.gov/pubmed/11073222
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